2,3-Diaminobenzoic acid methyl ester → Methyl-2-trichloromethyl-1H-benzoimidazole-4-carboxylate

HRID 18516

반응식

HRID 18516 반응식
COC([C:5]1[CH:17]=[CH:16][C:8]2[NH:9][C:10]([C:12]([Cl:15])([Cl:14])[Cl:13])=[N:11][C:7]=2[CH:6]=1)=O.[CH3:18][O:19][C:20](=[O:29])C1C=CC=C(N)C=1N>>[CH3:18][O:19][C:20]([C:16]1[C:8]2[N:9]=[C:10]([C:12]([Cl:13])([Cl:14])[Cl:15])[NH:11][C:7]=2[CH:6]=[CH:5][CH:17]=1)=[O:29]

참가 물질

3

반응물 2

HCID 5718252,3-Diaminobenzoic acid methyl esterHCID 178497356HCID 178497356, 화합물

생성물 1

HCID 23033456Methyl-2-trichloromethyl-1H-benzoimidazole-4-carboxylate

실험 절차

Methyl-2-trichloromethyl-1H-benzoimidazole-4-carboxylate was prepared similarly to methyl-2-trichloromethyl-1H-benzoimidazole-5-carboxylate as described in example 5 i) starting from 2.53 g (15.1 mmol) methyl-2,3-diamino-benzoate. Yield: 4.15 g MS (ES+): m/e=293, chloro pattern.

출처 및 근거

ORD 기록
ord-94d69d9284704f0183262257660df5ab
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07741341B2

연결된 노트

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