Potassium Carbonate → HCID 59633880, 화합물

HRID 1852585노트

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HRID 1852585 반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:17]3[C:12](=[CH:13][C:14]([C:18]([O:20][CH3:21])=[O:19])=[CH:15][CH:16]=3)[CH:11]=[CH:10]2)=[CH:5][C:4]=1F)#[N:2].[C:23]([O-])([O-])=[O:24].[K+].[K+]>CO.O>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[C:17]3[C:12](=[CH:13][C:14]([C:18]([O:20][CH3:21])=[O:19])=[CH:15][CH:16]=3)[CH:11]=[CH:10]2)=[CH:5][C:4]=1[O:24][CH3:23])#[N:2]

참가 물질

5

반응물 2

HCID 11430Potassium CarbonateHCID 59633877HCID 59633877, 화합물

생성물 1

HCID 59633880HCID 59633880, 화합물수율 102%

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

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온도
75 °C

실험 절차

A solution of 95 mg (0.32 mmol) of compound 9m was combined with 120 mg (0.87 mmol) of K2CO3 in 8 mL of MeOH and heated at 75° C. for 5 h. The mixture was cooled, diluted with water, and extracted with CH2Cl2. The organic solution was concentrated to give 100 mg (100%) of 9n as a white solid.

후처리

  1. temperatureThe mixture was cooled
  2. extractionextracted with CH2Cl2
  3. concentrationThe organic solution was concentrated

출처 및 근거

ORD 기록
ord-db22ec1412404d8da633b9aa9d3a11d5
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08962607B2

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