Aluminium lithium hydride → HCID 178461264, 화합물

HRID 1852697노트

반응식

HRID 1852697 반응식
[H-].[H-].[H-].[H-].[Li+].[Al+3].CC1C=CC(S([O:17][CH2:18][C@H:19]2[CH2:24][CH2:23][C@H:22]([CH2:25]O)[CH2:21][CH2:20]2)(=O)=O)=CC=1>C1COCC1>[CH3:25][C@H:22]1[CH2:23][CH2:24][C@H:19]([CH2:18][OH:17])[CH2:20][CH2:21]1

참가 물질

4

반응물 2

HCID 21226445Aluminium lithium hydrideHCID 178427753HCID 178427753, 화합물

생성물 1

HCID 178461264HCID 178461264, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

LiAlH4 (153 g, 4 mol) was added to a solution of trans-4-(hydroxymethyl)cyclohexylmethyl 4-methylbenzenesulfonate (400 g, 1.34 mol) in THF (3000 mL) at −20° C. The mixture was stirred at room temperature for 3 h. It was quenched with water (10 L) and filtered. The filtrate was concentrated in vacuo to give trans-(4-methylcyclohexyl)methanol.

후처리

  1. customIt was quenched with water (10 L)
  2. filtrationfiltered
  3. concentrationThe filtrate was concentrated in vacuo

출처 및 근거

ORD 기록
ord-7ad4ea22f3614ae0b4df3563aec2ca6c
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08962611B2

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