Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Toluene → Benzimidazole, 2-trichloromethyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Toluene | HCID 1140 | — |
| 반응물 | O-Phenylenediamine | HCID 7243 | — |
| 반응물 | Methyl 2,2,2-trichloroacetimidate | HCID 100479 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | Benzimidazole, 2-trichloromethyl- | HCID 77133 | — |
반응 단계
To a solution of 10 g Benzene-1,2-diamine in 250 mL acetic acid, 22.8 g 2,2,2-Trichloro-acetimidic acid methyl ester were added drop wise at RT. After 2 h 500 mL toluene were added and the solvents were removed under reduced pressure. The residue was codestilled additional two times with toluene. After drying under reduced pressure the product was pure enough for the next reaction step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741341B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-0afa7b3ef23347f6a27ba72298be89b9 |
| 출처 메모 | uspto-grants-2010_06 |