Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-(2-Methoxyethoxy)-6-nitroaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Bromoethyl methyl ether | HCID 80972 | — |
| 반응물 | 2-Amino-3-Nitrophenol | HCID 4115495 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(2-Methoxyethoxy)-6-nitroaniline | HCID 59349604 | — |
반응 단계
A solution of 5 g 2-Amino-3-nitro-phenol, 4.5 g 1-Bromo-2-methoxy-ethane, 4.4 g K2CO3 in 50 mL DMF were heated to 60° C. for 16 h. Then 50 mL of water were added and the mixture was extracted with ethyl acetate (3×100 ml). The combined organic layers were dried over MgSO4, and the solvents were removed under reduced pressure. The remaining product was pure enough for the next reaction step. Yield: 5.8 g.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741341B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-e4212dad419940b0b09a993a75280f66 |
| 출처 메모 | uspto-grants-2010_06 |