Tert-Butylamine → 5-(tert-Butyl)-3-((tert-butylamino)methyl)-2'-chloro-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ol hydrochloride
반응식
[C:1]([C:5]1[CH:6]=[C:7]([CH:23]=O)[C:8]([OH:22])=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][C:12]=2[Cl:21])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[C:25]([NH2:29])([CH3:28])([CH3:27])[CH3:26]>>[ClH:21].[C:1]([C:5]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:18])[F:19])=[CH:13][C:12]=2[Cl:21])[C:8]([OH:22])=[C:7]([CH2:23][NH:29][C:25]([CH3:28])([CH3:27])[CH3:26])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2]참가 물질
3
실험 절차
5-(tert-Butyl)-3-((tert-butylamino)methyl)-2′-chloro-4′-(trifluoromethyl)-[1,1′-biphenyl]-2-ol hydrochloride was prepared as a white solid using the procedure described in Example 9 from 5-(tert-butyl)-2′-chloro-2-hydroxy-4′-(trifluoromethyl)-[1,1′-biphenyl]-3-carbaldehyde and tert-butylamine.
출처 및 근거
- ORD 기록
- ord-ec404715a197499485943955f98d44de
- 출처 데이터셋
- uspto-grants-2015_02