Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → N,N-bis(2-chloroethyl)methyl ammonium hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | N-Methyldiethanolamine | HCID 7767 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | N,N-bis(2-chloroethyl)methyl ammonium hydrochloride | HCID 71676372 | 85% |
반응 단계
A solution of N-methyldiethanolamine (3 g, 25 mmol) in CH2Cl2 (5 mL) was slowly added dropwise to thionyl chloride (10 mL) in ice-water bath, then stirred at r. t. for 2 days. After evaporated, the residue was dispersed with CH3CN/Et2O, then was filtered to give N,N-bis(2-chloroethyl)methyl ammonium hydrochloride (4.1 g, 85%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08962670B2 |
| 출처 데이터셋 | uspto-grants-2015_02 |
| ORD ID | ord-441c7afbe3b5454e9271c4cc512024cc |
| 출처 메모 | uspto-grants-2015_02 |