HCID 68632008, 화합물 → HCID 57829808, 화합물

반응식

CN(C)[CH:3]=[C:4]([C:8]1[O:12][N:11]=[C:10]([CH3:13])[N:9]=1)[C:5](=O)[CH3:6].[N+]([O-])(O)=O.[N+]([O-])(O)=O.[CH3:23][O:24][C:25]1[CH:26]=[C:27]([NH:37][C:38]([NH2:40])=[NH:39])[CH:28]=[CH:29][C:30]=1[N:31]1[CH:35]=[C:34]([CH3:36])[N:33]=[CH:32]1>>[CH3:23][O:24][C:25]1[CH:26]=[C:27]([NH:37][C:38]2[N:40]=[C:5]([CH3:6])[C:4]([C:8]3[O:12][N:11]=[C:10]([CH3:13])[N:9]=3)=[CH:3][N:39]=2)[CH:28]=[CH:29][C:30]=1[N:31]1[CH:35]=[C:34]([CH3:36])[N:33]=[CH:32]1

참가 물질

반응물 2

HCID 68632008HCID 68632008, 화합물

HCID 178493228HCID 178493228, 화합물

생성물 1

HCID 57829808HCID 57829808, 화합물

실험 절차

The title compound was prepared from crude 4-dimethylamino-3-(3-methyl-[1,2,4]oxadiazol-5-yl)-but-3-en-2-one (313 mg, 1.6 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (297 mg, 0.8 mmol) using in analogous manner the procedure described in example 39b). Obtained as a pale-yellow solid (142 mg, 47%).

출처 및 근거

ORD 기록: ord-ea21d87b0e754512a54d9eb9d1a98f22
출처 데이터셋: uspto-grants-2015_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08962834B2

반응 노트

불러오는 중…