Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → (1,1'-Biphenyl)-4-butanoic acid, gamma-hydroxy-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Fenbufen | HCID 3335 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | (1,1'-Biphenyl)-4-butanoic acid, gamma-hydroxy- | HCID 16072199 | — |
반응 단계
A 25.4 g. portion of 3-(4-biphenylylcarbonyl)propionic acid is dissolved in 2 liters of water made alkaline with sodium hydroxide. A 37.8 g. portion of sodium borohydride is added and the mixture is stirred for 2 hours. The suspension is then slowly poured into 100 ml. of glacial acetic acid. The mixture is cooled and the resulting solid is filtered, washed with water and dried giving the desired product, m.p. 139°-140° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04219668 |
| 출처 데이터셋 | uspto-grants-1980_08 |
| ORD ID | ord-683b6ab37ab6474ab8171af01f918ae9 |
| 출처 메모 | uspto-grants-1980_08 |