Water → 2,2'-(2,5-Dioxopiperazine-1,4-diyl)diacetic acid

HRID 1859259노트

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HRID 1859259 반응식
[C:1]([N:4]([CH2:9][C:10]([OH:12])=O)[CH2:5][C:6]([OH:8])=[O:7])(=[O:3])[CH3:2].[OH2:13]>C(O)(=O)C>[C:6]([CH2:5][N:4]1[CH2:2][C:1](=[O:3])[N:4]([CH2:5][C:6]([OH:8])=[O:7])[CH2:9][C:10]1=[O:12])([OH:7])=[O:13]

참가 물질

4

반응물 2

HCID 962WaterHCID 10130190N-acetyliminodiacetic acid

생성물 1

HCID 235108522,2'-(2,5-Dioxopiperazine-1,4-diyl)diacetic acid

시약·촉매·용매 1

HCID 176Acetic Acid용매

반응 조건

온도
195 °C

실험 절차

N-acetyliminodiacetic acid (XVI) monohydrate (45 g) and varying amounts of water and acetic acid were heated at 175° C. or 195° C. for various periods of time. After cooling to room temperature, the mixture was filtered. The solid was washed with water (10 mL) and dried to give 1,4-di(carboxymethyl)-2,5-diketopiperazine. The table below shows the yields of solid under various conditions.

후처리

  1. temperatureAfter cooling to room temperature
  2. filtrationthe mixture was filtered
  3. washThe solid was washed with water (10 mL)
  4. customdried

출처 및 근거

ORD 기록
ord-17dfbc30ca9d4fd8b1bb1863a4fe8c94
출처 데이터셋
uspto-grants-2000_11
특허 번호
US06153753

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