Pyridine → 6-tert-Butyl-5-(toluene-4-sulfonylsulfanyl)-2,3-dihydro-indole-1-carboxylic Acid Tert-Butyl Ester

HRID 1859552

반응식

HRID 1859552 반응식
[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([SH:21])=[C:14]([C:17]([CH3:20])([CH3:19])[CH3:18])[CH:15]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].N1C=CC=CC=1.[S:28](Br)([C:31]1[CH:37]=[CH:36][C:34]([CH3:35])=[CH:33][CH:32]=1)(=[O:30])=[O:29].C(Cl)(Cl)(Cl)Cl>CCOC(C)=O>[C:1]([O:5][C:6]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([S:21][S:28]([C:31]3[CH:37]=[CH:36][C:34]([CH3:35])=[CH:33][CH:32]=3)(=[O:30])=[O:29])=[C:14]([C:17]([CH3:20])([CH3:19])[CH3:18])[CH:15]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]

참가 물질

6

반응물 4

HCID 1049PyridineHCID 5943Carbon TetrachlorideHCID 101308854-Methylbenzene-1-sulfonyl bromideHCID 540779236-tert-Butyl-5-mercapto-2,3-dihydro-indole-1-carboxylic Acid Tert-Butyl Ester

생성물 1

HCID 570442746-tert-Butyl-5-(toluene-4-sulfonylsulfanyl)-2,3-dihydro-indole-1-carboxylic Acid Tert-Butyl Ester

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

The title compound was prepared according to General Method 15 using 6-tert-Butyl-5-mercapto-2,3-dihydro-indole-1-carboxylic acid tert-butyl ester (prepared in Example FF), pyridine, tosyl bromide, carbon tetrachloride, and EtOAc.

출처 및 근거

ORD 기록
ord-ac07f963328449e4a7a2cfc242a4e78d
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06528510B1

연결된 노트

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