3,5-Dichlorophenyl isothiocyanate → HCID 18626209, 화합물

HRID 1859712

반응식

HRID 1859712 반응식
[NH2:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][C:18]=1[O:19][CH3:20])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([Cl:14])=[C:10]([Cl:15])[CH:9]=1)=[O:6].[Cl:21][C:22]1[CH:23]=[C:24]([N:29]=[C:30]=[S:31])[CH:25]=[C:26]([Cl:28])[CH:27]=1>>[Cl:15][C:10]1[CH:9]=[C:8]([NH:7][C:5](=[O:6])[C:4]2[CH:16]=[CH:17][C:18]([O:19][CH3:20])=[C:2]([NH:1][C:30]([NH:29][C:24]3[CH:25]=[C:26]([Cl:28])[CH:27]=[C:22]([Cl:21])[CH:23]=3)=[S:31])[CH:3]=2)[CH:13]=[CH:12][C:11]=1[Cl:14]

참가 물질

3

반응물 2

HCID 1387763,5-Dichlorophenyl isothiocyanateHCID 99486273-Amino-4-methoxy-N-(3,4-dichlorophenyl)-benzamide

생성물 1

HCID 18626209HCID 18626209, 화합물수율 50.4%

실험 절차

Prepared according to the procedure described for Example 78 using 3-amino-4-methoxy-N-(3,4-dichloro-phenyl)-benzamide from Example 4 (0.932 g, 3.00 mmol) and 3,5-dichlorophenyl isothiocyanate (0.335 g, 1.64 mmol). After 2 days, filtration afforded the product (0.426 g); m.p. 189-191° C.

후처리

  1. customPrepared
  2. filtrationfiltration

출처 및 근거

ORD 기록
ord-673c403691194f3a9d1c8cd1481aa47a
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06528528B2

연결된 노트

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