Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Amino-4-methoxybenzanilide → 3-(2,4-Difluoro-benzenesulfonylamino)-4-methoxy-N-phenyl-benzamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Amino-4-methoxybenzanilide | HCID 8426 | — |
| 반응물 | 2,4-Difluorobenzenesulfonyl Chloride | HCID 2734273 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | 3-(2,4-Difluoro-benzenesulfonylamino)-4-methoxy-N-phenyl-benzamide | HCID 18626262 | 84.4% |
반응 단계
Prepared according to the procedure described for Example 121 using 2,4-difluorobenzenesulfonyl chloride (2.19 g, 10 mmol), 3-amino-4-methoxy-N-phenyl-benzamide (2.43 g, 10 mmol), and pyridine (25 mL) to afford the product (3.532 g); m.p. 198-200° C. after trituration in hexanes/ethyl acetate (1:1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06528528B2 |
| 출처 데이터셋 | uspto-grants-2003_03 |
| ORD ID | ord-8e0a43a66efd4394b446b0f70e7fd65c |
| 출처 메모 | uspto-grants-2003_03 |