4-Formylbenzamide → HCID 178479545, 화합물

HRID 1859795노트

반응식

HRID 1859795 반응식
[ClH:1].[NH:2]1[CH:6]=[C:5]([CH2:7][CH2:8][O:9][C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[C:16](=[O:20])[CH2:15][CH2:14][CH2:13]3)[N:4]=[CH:3]1.[CH:21]1[C:26]([CH:27]=O)=[CH:25][CH:24]=[C:23]([C:29]([NH2:31])=[O:30])[CH:22]=1>[OH-].[K+].CCO>[ClH:1].[NH:2]1[CH:6]=[C:5]([CH2:7][CH2:8][O:9][C:10]2[CH:11]=[C:12]3[C:17](=[CH:18][CH:19]=2)[C:16](=[O:20])[C:15](=[CH:27][C:26]2[CH:25]=[CH:24][C:23]([C:29]([NH2:31])=[O:30])=[CH:22][CH:21]=2)[CH2:14][CH2:13]3)[N:4]=[CH:3]1

참가 물질

5

반응물 2

HCID 117447904-FormylbenzamideHCID 178479625HCID 178479625, 화합물

생성물 1

HCID 178479545HCID 178479545, 화합물

시약·촉매·용매 2

HCID 702Ethanol용매HCID 14797Potassium Hydroxide용매

실험 절차

According to the method of Example 34, 6-[2-(1H-imidazole-4-yl)-ethoxy]-3,4-dihydro-2H-naphthalen-1-one, monohydrochloride (0.313 g, 1.07 mmol) was reacted with benzamide-4-carboxaldehyde (0.178 g, 1.13 mmol) in 5 mL of 4% KOH in EtOH overnight to afford 0.197 (42%) of the title compound as an off-white powder, mp dec. >230° C.: CI-MS m/e 388 (M++1).

출처 및 근거

ORD 기록
ord-4cd3cade7bcc4d8eb83080be1ba48c76
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06528535B2

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