Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Methyl 3-trifluoromethylpyridine-6-ylbenzoate | HCID 18625897 | — |
| 생성물 | 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid | HCID 22736909 | 72.7% |
반응 단계
In a similar manner to that described in Example 2, a reaction was carried out using methyl 3-trifluoromethylpyridine-6-ylbenzoate (791 mg) and aqueous sodium hydroxide solution (1N, 5.60 ml) and the reaction mixture was treated to afford the title compound (546 mg) which includes some impurity and was used in example 106 without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06528525B1 |
| 출처 데이터셋 | uspto-grants-2003_03 |
| ORD ID | ord-c54feab767b34f7c8e3d3a9cfdd867f1 |
| 출처 메모 | uspto-grants-2003_03 |