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HRID 1860052생성일: 2026년 10월 26일

Sodium Hydroxide → 2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acid

https://huagongshe.com/reaction/1860052

반응식

참여 물질

역할이름HCID투입량
반응물Sodium HydroxideHCID 14798—
반응물Methyl 3-trifluoromethylpyridine-6-ylbenzoateHCID 18625897—
생성물2-(5-(Trifluoromethyl)pyridin-2-yl)benzoic acidHCID 2273690972.7%

반응 단계

In a similar manner to that described in Example 2, a reaction was carried out using methyl 3-trifluoromethylpyridine-6-ylbenzoate (791 mg) and aqueous sodium hydroxide solution (1N, 5.60 ml) and the reaction mixture was treated to afford the title compound (546 mg) which includes some impurity and was used in example 106 without further purification.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06528525B1
출처 데이터셋uspto-grants-2003_03
ORD IDord-c54feab767b34f7c8e3d3a9cfdd867f1
출처 메모uspto-grants-2003_03