ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate → HCID 9835275, 화합물

HRID 1860538노트

반응식

HRID 1860538 반응식
C(OC(C1CCC2C(=CC=CC=2)C1=O)=O)C.C(OC(C1CCC2C(=CC=C(Cl)C=2)C1=O)=O)C.[OH:34][NH:35][C:36](=[O:54])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH:42]1[CH2:51][CH2:50][C:49]2[C:44](=[CH:45][CH:46]=[C:47](Cl)[CH:48]=2)[C:43]1=[O:53]>>[OH:34][NH:35][C:36](=[O:54])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH:42]1[CH2:51][CH2:50][C:49]2[C:44](=[CH:45][CH:46]=[CH:47][CH:48]=2)[C:43]1=[O:53]

참가 물질

4

반응물 3

HCID 251472ethyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylateHCID 21218215HCID 21218215, 화합물HCID 229774506-(6-chloro-1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-hexanoic Acid Hydroxyamide

생성물 1

HCID 9835275HCID 9835275, 화합물

실험 절차

6-(1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-hexanoic acid hydroxyamide (5a) is prepared from 1-oxo-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid ethyl ester (1a) in an analogous manner to that described for the conversion of 3a to 3c in example 3. Yield in the last step is 10%, MS (APCI): 274.1 (M−1).

후처리

  1. customYield in the last step

출처 및 근거

ORD 기록
ord-7dc7e151016c40f5848c436cfe25d342
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06531472B2

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