Piperidine → HCID 10154512, 화합물

반응식

[CH:1]1([CH2:4][N:5]2[C:14](=[O:15])[C:13]3[NH:12][C:11](Br)=[N:10][C:9]=3[N:8]([CH2:17][CH:18]3[CH2:20][CH2:19]3)[C:6]2=[O:7])[CH2:3][CH2:2]1.[NH:21]1[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]1>>[CH:1]1([CH2:4][N:5]2[C:14](=[O:15])[C:13]3[NH:12][C:11]([N:21]4[CH2:26][CH2:25][CH2:24][CH2:23][CH2:22]4)=[N:10][C:9]=3[N:8]([CH2:17][CH:18]3[CH2:20][CH2:19]3)[C:6]2=[O:7])[CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 8082Piperidine

HCID 15291302HCID 15291302, 화합물

생성물 1

HCID 10154512HCID 10154512, 화합물

실험 절차

The title compound was prepared from 1,3-di-cyclo-propylmethyl-8-bromo xanthine (1.2 g, 0.0037 mol) and piperidine (0.79 g, 0.009 mol) using an analogous procedure to that described in Example 19. The title product was obtained as a crystalline solid, m.pt. >250° C.

출처 및 근거

ORD 기록: ord-35936c28cf714d6eb6c636fcc4f94460
출처 데이터셋: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06531600B1

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