Acetyl chloride → Hydroxyethylidenediphosphonic acid

HRID 1861597

반응식

HRID 1861597 반응식
[P:1]([O:12][Si](C)(C)C)([O:7][Si](C)(C)C)[O:2][Si](C)(C)C.[C:17](Cl)(=[O:19])[CH3:18]>CO>[OH:19][CH2:17][CH:18]([P:1](=[O:2])([OH:12])[OH:7])[P:1](=[O:12])([OH:7])[OH:2]

참가 물질

4

반응물 2

HCID 6367Acetyl chlorideHCID 137213Tris(trimethylsilyl) phosphite

생성물 1

HCID 9977539Hydroxyethylidenediphosphonic acid

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Tris(trimethylsilyl) phosphite (2 molar equiv.) in an appropriate dry solvent was added dropwise to a stirred solution of acetyl chloride (1 molar equiv.) in an appropriate dry solvent at room temperature and the mixture stirred for 10 minutes. Excess methanol was then added and the mixture stirred for 5 minutes to decompose the silyl esters. The volatile components in the reaction mixture were then removed under reduced pressure to leave the title compound in good purity.

후처리

  1. stirringthe mixture stirred for 5 minutes
  2. customThe volatile components in the reaction mixture were then removed under reduced pressure

출처 및 근거

ORD 기록
ord-f82e89ad44eb4d42a5e41a178cb7c5fd
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06534488B1

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