Ethyl 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate → 4-(2-Cyclopropylmethoxy-4-fluoro-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ethyl ester

반응식

[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][nH:8][c:9]2[c:10]1[n:11][cH:12][n:13][c:14]2[Cl:15].[CH:16]1([CH2:19][O:20][c:21]2[c:22]([B:28]3[O:29][C:30]([CH3:31])([CH3:32])[C:33]([CH3:34])([CH3:35])[O:36]3)[cH:23][cH:24][c:25]([F:27])[cH:26]2)[CH2:17][CH2:18]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][nH:8][c:9]2[c:10]1[n:11][cH:12][n:13][c:14]2-[c:22]1[c:21]([O:20][CH2:19][CH:16]2[CH2:17][CH2:18]2)[cH:26][c:25]([F:27])[cH:24][cH:23]1

참가 물질

반응물 2

HCID 52987614Ethyl 4-chloro-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylate

HCID 569236402-(2-(Cyclopropylmethoxy)-4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

생성물 1

HCID 668665534-(2-Cyclopropylmethoxy-4-fluoro-phenyl)-5H-pyrrolo[3,2-d]pyrimidine-7-carboxylic acid ethyl ester

출처 및 근거

ORD 기록: ord-6a721f57b1b045f58351b91e7e91bb14
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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