1,4-Dioxa-8-azaspiro(4.5)decane → N-(4-{[2-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)pyrimidin-4-yl]oxy}-1-naphthyl)-3-fluoro-5-morpholin-4-ylbenzamide

HRID 186213

반응식

HRID 186213 반응식
[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][cH:10][c:11]([O:18][c:19]3[n:20][c:21]([S:25]([CH3:26])(=[O:27])=[O:28])[n:22][cH:23][cH:24]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[cH:29][c:30]([N:32]2[CH2:33][CH2:34][O:35][CH2:36][CH2:37]2)[cH:31]1.[O:38]1[CH2:39][CH2:40][O:41][C:42]12[CH2:43][CH2:44][NH:45][CH2:46][CH2:47]2>>[F:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[NH:7][c:8]2[cH:9][cH:10][c:11]([O:18][c:19]3[n:20][c:21]([N:45]4[CH2:44][CH2:43][C:42]5([O:38][CH2:39][CH2:40][O:41]5)[CH2:47][CH2:46]4)[n:22][cH:23][cH:24]3)[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]23)[cH:29][c:30]([N:32]2[CH2:33][CH2:34][O:35][CH2:36][CH2:37]2)[cH:31]1

참가 물질

3

반응물 2

HCID 674351,4-Dioxa-8-azaspiro(4.5)decaneHCID 595530953-fluoro-N-(4-{[2-(methylsulfonyl)pyrimidin-4-yl]oxy}-1-naphthyl)-5-morpholin-4-ylbenzamide

생성물 1

HCID 59553139N-(4-{[2-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)pyrimidin-4-yl]oxy}-1-naphthyl)-3-fluoro-5-morpholin-4-ylbenzamide

출처 및 근거

ORD 기록
ord-582427c4153a454c81a2dcfcd7a9c05f
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

연결된 노트

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