HCID 11063236, 화합물 → Ethyl 2-(1-cyanocyclohexyl)acetate

HRID 1862576노트

반응식

HRID 1862576 반응식
[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH:11]=[CH:10][CH2:9][CH:8]=[CH:7]1)[CH3:2]>[Pd].CO>[CH2:1]([O:3][C:4](=[O:14])[CH2:5][C:6]1([C:12]#[N:13])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1)[CH3:2]

참가 물질

4

반응물 1

HCID 11063236HCID 11063236, 화합물

생성물 1

HCID 10965422Ethyl 2-(1-cyanocyclohexyl)acetate수율 94.3%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

Added 1% Pd/C catalyst (1.67 g, 0.157 mmol) to a solution of (1-cyanocyclohexa-2,5-dienyl)acetic acid ethyl ester (3.00 g, 15.7 mmol) in MeOH (75 mL). After shaking the reaction under 20 psi H2 at room temperature for 2 hours, the pressure was slowly released. The reaction was filtered and concentrated under reduced pressure to afford 2.89 g (94%) of product as an oil.

후처리

  1. customthe reaction under 20 psi H2 at room temperature for 2 hours
  2. filtrationThe reaction was filtered
  3. concentrationconcentrated under reduced pressure

출처 및 근거

ORD 기록
ord-a26f848a323241d9b785d8e9c5cd2aae
출처 데이터셋
uspto-grants-2003_03
특허 번호
US06538148B2

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