Bisphenol A diglycidyl ether → 2,2-Bis[4-{2-hydroxy-3-[N-octyl-N-(2,2,6,6-tetramethyl-4-piperidyl)amino]propoxy}phenyl]propane

HRID 1862924노트

반응식

HRID 1862924 반응식
[CH3:1][C:2]1([CH3:19])[CH2:7][CH:6]([NH:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:5][C:4]([CH3:18])([CH3:17])[NH:3]1.[O:20]1[CH2:44][CH:21]1[CH2:22][O:23][C:24]1[CH:29]=[CH:28][C:27]([C:30]([C:33]2[CH:38]=[CH:37][C:36]([O:39][CH2:40][CH:41]3[O:43][CH2:42]3)=[CH:35][CH:34]=2)([CH3:32])[CH3:31])=[CH:26][CH:25]=1>CO>[OH:43][CH:41]([CH2:42][N:8]([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH:6]1[CH2:7][C:2]([CH3:1])([CH3:19])[NH:3][C:4]([CH3:17])([CH3:18])[CH2:5]1)[CH2:40][O:39][C:36]1[CH:37]=[CH:38][C:33]([C:30]([C:27]2[CH:28]=[CH:29][C:24]([O:23][CH2:22][CH:21]([OH:20])[CH2:44][N:8]([CH:6]3[CH2:5][C:4]([CH3:18])([CH3:17])[NH:3][C:2]([CH3:19])([CH3:1])[CH2:7]3)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])=[CH:25][CH:26]=2)([CH3:32])[CH3:31])=[CH:34][CH:35]=1

참가 물질

4

반응물 2

HCID 2286Bisphenol A diglycidyl etherHCID 143651212,2,6,6-Tetramethyl-4-octylaminopiperidine

생성물 1

HCID 203935552,2-Bis[4-{2-hydroxy-3-[N-octyl-N-(2,2,6,6-tetramethyl-4-piperidyl)amino]propoxy}phenyl]propane

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of 13 g of 2,2,6,6-tetramethyl-4-octylaminopiperidine and 8 g of 2,2-bis[p-(2,3-epoxypropoxy)phenyl]propane in 200 ml of methanol was refluxed, with stirring, for 6 hours. At the end of this time, the solvent was removed from the residue by evaporation under reduced pressure, leaving a residue, which was purified by column chromatography through silica gel eluted with a 20:4:2:1 by volume mixture of ethyl acetate, benzene, ethanol and triethylamine. The desired compound was obtained in the form of a colourless, transparent, very viscous liquid having an Rf value of 0.27 on thin layer chromatography on silica gel developed with a 20:4:2:1 by volume mixture of ethyl acetate, benzene, ethanol and triethylamine.

후처리

  1. temperaturewas refluxed
  2. customAt the end of this time, the solvent was removed from the residue by evaporation under reduced pressure
  3. customleaving a residue, which
  4. customwas purified by column chromatography through silica gel
  5. washeluted with a 20:4:2:1 by volume mixture of ethyl acetate, benzene, ethanol and triethylamine

출처 및 근거

ORD 기록
ord-2080dc1dcd4c466293156d8a2a4a013e
출처 데이터셋
uspto-grants-1979_09
특허 번호
US04166813

반응 노트

불러오는 중…