4-Chloro-5-fluoro-2-propylpyridine → 4-Chloro-3,5-difluoro-2-propyl-pyridine

HRID 1864

반응식

HRID 1864 반응식
ClC1C([F:8])=CN=C(C)C=1.[Cl:10][C:11]1[C:16]([F:17])=[CH:15][N:14]=[C:13]([CH2:18][CH2:19][CH3:20])[CH:12]=1>>[Cl:10][C:11]1[C:16]([F:17])=[CH:15][N:14]=[C:13]([CH2:18][CH2:19][CH3:20])[C:12]=1[F:8]

참가 물질

3

반응물 2

HCID 196912934-Chloro-5-fluoro-2-propylpyridine2회HCID 196914104-Chloro-5-fluoro-2-methylpyridine2회

생성물 1

HCID 196913534-Chloro-3,5-difluoro-2-propyl-pyridine

실험 절차

By following the procedures described in Example 69 and replacing 4-chloro-5-fluoro-2-picoline (the product of Example 66) with 4-chloro-5-fluoro-2-propyl-pyridine (the product of Example 70), the title compound can be prepared.

출처 및 근거

ORD 기록
ord-cf330283adb847978dd3b58700a37b8c
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05726182

연결된 노트

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