2-Amino-N-phenylbenzamide → 2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide

반응식

[NH2:1][C:2]1[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=1[C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)=[O:5].[Cl:17][C:18]1[N:23]=[C:22](Cl)[C:21]([Cl:25])=[CH:20][N:19]=1>>[Cl:17][C:18]1[N:23]=[C:22]([NH:1][C:2]2[CH:16]=[CH:15][CH:14]=[CH:13][C:3]=2[C:4]([NH:6][C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)=[O:5])[C:21]([Cl:25])=[CH:20][N:19]=1

참가 물질

반응물 2

HCID 781422-Amino-N-phenylbenzamide

HCID 2372592,4,5-Trichloropyrimidine

생성물 1

HCID 579741332-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide

실험 절차

2-[(2,5-Dichloro-4-pyrimidinyl)amino]-N-phenylbenzamide was prepared from 2-amino-N-phenylbenzamide and 2,4,5-trichloropyrimidine using a procedure substantially as described for the preparation of Intermediate 1. Mass (M+H)+=358, 360.

출처 및 근거

ORD 기록: ord-5f8449f0af6b482baa4d2a72bc99559a
출처 데이터셋: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07625903B2

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