Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(3-(Trifluoromethyl)phenyl)piperazine → (RS)-1-(3-Methoxy-benzenesulfonyl)-3-phenyl-4-[4-(3-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-imidazolidin-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(3-(Trifluoromethyl)phenyl)piperazine | HCID 4296 | — |
| 반응물 | (RS)-1-(3-methoxy-benzenesulfonyl)-2-oxo-3-phenyl-imidazolidine-4-carboxylic acid | HCID 67141122 | — |
| 생성물 | (RS)-1-(3-Methoxy-benzenesulfonyl)-3-phenyl-4-[4-(3-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-imidazolidin-2-one | HCID 25027710 | — |
반응 단계
In analogy to example 1, (RS)-1-(3-methoxy-benzenesulfonyl)-2-oxo-3-phenyl-imidazolidine-4-carboxylic acid (step 4 of example 1) was reacted with N-(3-trifluoromethylphenyl)-piperazine to give the title compound as a colorless solid. MS: 588.5 ([M+H]+)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07625902B2 |
| 출처 데이터셋 | uspto-grants-2009_12 |
| ORD ID | ord-75f78c18f62f4916981b147fe201158d |
| 출처 메모 | uspto-grants-2009_12 |