Allyl bromide → Methyl 2-(allyloxy)-4-methoxybenzoate

참여 물질

역할	이름	HCID	투입량
반응물	Allyl bromide	HCID 7841	—
반응물	Cesium carbonate	HCID 10796	—
반응물	Methyl 4-methoxysalicylate	HCID 79523	—
용매	Dimethylformamide	HCID 6228	—
용매	Ethyl Acetate	HCID 8857	—
생성물	Methyl 2-(allyloxy)-4-methoxybenzoate	HCID 10242646	—

반응 단계

To a solution of methyl 4-methoxysalicylate (2.0 g, 11 mmol) in DMF (20 mL) at room temperature was added Cs2CO3 (1.3 eq, 4.7 g) and allyl bromide (1.3 eq, 1.23 mL). After 2 hr, reaction mixture was diluted with EtOAc and washed with water (3×), brine (1×). The organic layer was dried over Na2SO4 and concentrated to provide the product as a pale yellow oil. Product was used without further purification.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07625933B2
출처 데이터셋	uspto-grants-2009_12
ORD ID	ord-d59ac7b80e7844719da3b652a4e54201
출처 메모	uspto-grants-2009_12