Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl vinyl ketone → 1-{4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl vinyl ketone | HCID 6570 | — |
| 반응물 | o-Fluorobenzaldehyde | HCID 67970 | — |
| 반응물 | 4-(Piperidine-1-sulfonyl)aniline | HCID 236648 | — |
| 생성물 | 1-{4-[2-(2-Fluoro-phenyl)-5-methyl-pyrrol-1-yl]-benzenesulfonyl}-piperidine | HCID 68487442 | — |
반응 단계
2-Fluorobenzaldehyde and but-3-en-2-one were treated according to the procedure outlined in General Procedure C followed by subjecting the resulting product to conditions outlined in General Procedure D along with p-piperidinylsulfonyl phenylamine to obtain the titled compound. 1H NMR (CDCl3) δ ppm 1.42-1.65 (6H), 2.15 (3H), 2.95 (4H), 6.15 (1H), 6.40 (1H), 6.65-7.90 (8H); MS (ESI) m/z 399 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741364B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-bb2f35b5a8f9432dbf27710baa7497c4 |
| 출처 메모 | uspto-grants-2010_06 |