Tosylacetonitrile → 2-(4-{2-Cyano-2-[(4-methylphenyl)sulfonyl]vinyl}phenyl)thiophene-3-carbonitrile

HRID 1865130

반응식

HRID 1865130 반응식
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:10][CH:11]=[CH:12][C:13]=2[C:14]#[N:15])=[CH:5][CH:4]=1)=O.[C:16]1([CH3:28])[CH:21]=[CH:20][C:19]([S:22]([CH2:25][C:26]#[N:27])(=[O:24])=[O:23])=[CH:18][CH:17]=1>>[C:26]([C:25]([S:22]([C:19]1[CH:20]=[CH:21][C:16]([CH3:28])=[CH:17][CH:18]=1)(=[O:24])=[O:23])=[CH:1][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:10][CH:11]=[CH:12][C:13]=2[C:14]#[N:15])=[CH:5][CH:4]=1)#[N:27]

참가 물질

3

반응물 2

HCID 79776TosylacetonitrileHCID 579749902-(4-Formylphenyl)thiophene-3-carbonitrile

생성물 1

HCID 690206312-(4-{2-Cyano-2-[(4-methylphenyl)sulfonyl]vinyl}phenyl)thiophene-3-carbonitrile

실험 절차

In a manner analogous to the procedure set forth in example A-239, the title compound is prepared from 2-(4-formylphenyl)thiophene-3-carbonitrile, prepared directly above, and p-toluenesulphonylacetonitrile.

출처 및 근거

ORD 기록
ord-f4ba3d13a87f4b0bba0be891fe90c47e
출처 데이터셋
uspto-grants-2009_12
특허 번호
US07625932B2

연결된 노트

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