Dimethylformamide → (S)-2-[3-(4-Cyclopropylcarbamoyl-thiazol-2-yl)-phenylcarbamoyl]-pyrrolidine-1-carboxylic acid benzyl ester

반응식

[CH2:1]([O:8][C:9]([N:11]1[CH2:15][CH2:14][CH2:13][C@H:12]1[C:16](=[O:33])[NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20](B2OC(C)(C)C(C)(C)O2)[CH:19]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:34]1([NH:37][C:38]([C:40]2[N:41]=[C:42](Br)[S:43][CH:44]=2)=[O:39])[CH2:36][CH2:35]1.C([O-])(O)=O.[Na+].CN(C=O)C>CO>[CH2:1]([O:8][C:9]([N:11]1[CH2:15][CH2:14][CH2:13][C@H:12]1[C:16](=[O:33])[NH:17][C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([C:42]2[S:43][CH:44]=[C:40]([C:38](=[O:39])[NH:37][CH:34]3[CH2:36][CH2:35]3)[N:41]=2)[CH:19]=1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1