Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Levofloxacin → Levofloxacin Hydrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Levofloxacin | HCID 149096 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | Levofloxacin Hydrate | HCID 3033924 | 118.5% |
반응 단계
1 g of levofloxacin crude was put in suspension in 7 ml of n-BuOH. The mixture was heated to reflux temperature until complete dissolution of the material. Then the solution was cooled to RT over a period of 2.5 hours. The precipitate was filtrated under vacuum, washed with n-BuOH and dried at 60° C. in a vacuum oven to give 810 mg (81%) of purified levofloxacin hemihydrate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07629458B2 |
| 출처 데이터셋 | uspto-grants-2009_12 |
| ORD ID | ord-eff9fbe4b7f54a919a865937573f56ab |
| 출처 메모 | uspto-grants-2009_12 |