3-(Morpholine-4-carbonyl)aniline → 4-(2-aminopyrimidin-5-yl)-N-[3-(morpholine-4-carbonyl)phenyl]-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidine-7-carboxamide

HRID 186695

반응식

[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][N:8]([CH2:9][c:10]2[cH:11][cH:12][c:13]([O:14][CH3:15])[cH:16][cH:17]2)[c:18]2[n:19][cH:20][c:21](-[c:22]3[c:23]4[c:27]([n:28][c:29]([N:30]5[CH2:31][CH2:32][O:33][CH2:34][CH2:35]5)[n:36]3)[NH:26][CH2:25][CH2:24]4)[cH:37][n:38]2)[cH:39][cH:40]1.[NH2:41][c:42]1[cH:43][c:44]([C:45]([N:46]2[CH2:47][CH2:48][O:49][CH2:50][CH2:51]2)=[O:52])[cH:53][cH:54][cH:55]1.[O:56]1[CH2:57][CH2:58][N:59]([C:62](=[O:63])[c:64]2[cH:65][c:66]([NH:70][C:71](=[O:72])[N:73]3[CH2:74][CH2:75][c:76]4[c:77]3[n:78][c:79]([N:107]3[CH2:108][CH2:109][O:110][CH2:111][CH2:112]3)[n:80][c:81]4-[c:82]3[cH:83][n:84][c:85]([N:88]([CH2:89][c:90]4[cH:91][cH:92][c:93]([O:94][CH3:95])[cH:96][cH:97]4)[CH2:98][c:99]4[cH:100][cH:101][c:102]([O:103][CH3:104])[cH:105][cH:106]4)[n:86][cH:87]3)[cH:67][cH:68][cH:69]2)[CH2:60][CH2:61]1>>[O:56]1[CH2:57][CH2:58][N:59]([C:62](=[O:63])[c:64]2[cH:65][c:66]([NH:70][C:71](=[O:72])[N:73]3[CH2:74][CH2:75][c:76]4[c:77]3[n:78][c:79]([N:107]3[CH2:108][CH2:109][O:110][CH2:111][CH2:112]3)[n:80][c:81]4-[c:82]3[cH:83][n:84][c:85]([NH2:88])[n:86][cH:87]3)[cH:67][cH:68][cH:69]2)[CH2:60][CH2:61]1

참가 물질

반응물 3

HCID 64850643-(Morpholine-4-carbonyl)aniline

HCID 45258862Bis-(4-methoxybenzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amine

HCID 140547145HCID 140547145, 화합물

생성물 1

HCID 592449934-(2-aminopyrimidin-5-yl)-N-[3-(morpholine-4-carbonyl)phenyl]-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidine-7-carboxamide

출처 및 근거

ORD 기록: ord-c70c6c6ff6c4405992e94aaf7dcb537b
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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