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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1867402생성일: 2026년 10월 25일

Piperidine, 1-(3-chloropropyl)- → 1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-one

https://huagongshe.com/reaction/1867402

반응식

참여 물질

역할이름HCID투입량
반응물Piperidine, 1-(3-chloropropyl)-HCID 79625—
반응물1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-oneHCID 62044921—
생성물1-[(E)-3-(3,4-Dichloro-phenyl)-acryloyl]-4-(3-piperidin-1-yl-propyl)-[1,4]diazepan-5-oneHCID 68431984—

반응 단계

In analogy to the procedure described in intermediate 4A, 1-[(E)-3-(3,4-dichloro-phenyl)-acryloyl]-[1,4]diazepan-5-one (intermediate 1A) and 1-(3-chloro-propyl)-piperidine gave the title compound as light yellow solid. MS: 438.1 (MH+, 2Cl).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07632829B2
출처 데이터셋uspto-grants-2009_12
ORD IDord-dffcd76c2a09470dad9f779a88f90324
출처 메모uspto-grants-2009_12