Trimethyl((tributylstannyl)ethynyl)silane → 2-(4-Hydroxyphenyl)-4-[(trimethylsilyl)ethynyl]quinolin-6-ol

참여 물질

역할	이름	HCID	투입량
반응물	Trimethyl((tributylstannyl)ethynyl)silane	HCID 639663	—
반응물	4-Bromo-2-(4-hydroxyphenyl)quinolin-6-ol	HCID 135454802	—
생성물	2-(4-Hydroxyphenyl)-4-[(trimethylsilyl)ethynyl]quinolin-6-ol	HCID 135409783	83%

반응 단계

This compound was prepared from 6a and (trimethylsilylethynyl)tributyltin according to method J. Yellow powder; Yield: 83%; mp 210° C. (dec.); 1H-NMR (300 MHz, acetone-d6) δ 0.38 (s, 9H), 7.02 (d, J=8.7 Hz, 2H), 7.44 (dd, J=9.1, 2.7 Hz, 1H), 7.63 (d, J=2.7 Hz, 1H), 7.99 (d, J=9.1 Hz, 1H), 8.05 (s, 1H), 8.18 (d, J=8.7 Hz, 2H), 8.70 (s, 1H), 9.15 (s, 1H); MS (ESI) m/z 332 ([M−H]−), 334 ([M+H]+); Anal. Calcd for C20H19NO2Si: C, 72.04; H, 5.74; N, 4.20. Found: C, 71.67; H, 5.79; N, 4.07.

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07632845B2
출처 데이터셋	uspto-grants-2009_12
ORD ID	ord-d17134ef89b64d14b2e74af40e954c34
출처 메모	uspto-grants-2009_12