5-Bromo-2,1,3-benzoxadiazole → 5Benzo[1,2,5]oxadiazol-5-yl-N-(2-fluoro-ethyl)-nicotinamide

HRID 1867512노트

반응식

HRID 1867512 반응식
Br[C:2]1[CH:3]=[CH:4][C:5]2[C:6]([CH:10]=1)=[N:7][O:8][N:9]=2.Br[C:12]1[CH:13]=[N:14][CH:15]=[C:16]([CH:23]=1)[C:17]([NH:19][CH2:20][CH2:21][F:22])=[O:18]>>[N:9]1[O:8][N:7]=[C:6]2[CH:10]=[C:2]([C:12]3[CH:13]=[N:14][CH:15]=[C:16]([CH:23]=3)[C:17]([NH:19][CH2:20][CH2:21][F:22])=[O:18])[CH:3]=[CH:4][C:5]=12

참가 물질

3

반응물 2

HCID 27762985-Bromo-2,1,3-benzoxadiazoleHCID 860043575-bromo-N-(2-fluoro-ethyl)-nicotinamide

생성물 1

HCID 860043545Benzo[1,2,5]oxadiazol-5-yl-N-(2-fluoro-ethyl)-nicotinamide

실험 절차

Starting from 5-bromo-benzo[1,2,5]oxadiazole and 5-bromo-N-(2-fluoro-ethyl)-nicotinamide. Beige powder. MS(ES−): 285 (M−1).

출처 및 근거

ORD 기록
ord-1791d9bcfb3345d787057a5d5e6885a2
출처 데이터셋
uspto-grants-2009_12
특허 번호
US07632851B2

반응 노트

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