Diethyl Ether → HCID 68508768, 화합물
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C([O:5][C:6]([N:8]1[C:12]([CH3:13])=[C:11]([Cl:14])[C:10]([C:15]([F:18])([F:17])[F:16])=[N:9]1)=[O:7])(C)(C)C.Cl.O1CCOCC1.CCOCC>ClCCl>[Cl:14][C:11]1[C:10]([C:15]([F:17])([F:16])[F:18])=[N:9][N:8]([C:6]([OH:7])=[O:5])[C:12]=1[CH3:13]참가 물질
5
실험 절차
To a stirred solution of 43.62 mmol of 4-chloro-5-methyl-3-trifluoromethylpyrazole-1-carboxylic acid tertbutyl ester in 20 mL of dichloromethane, carefully add 40 mL of 4M HCl/dioxane. The reaction mixture was allowed to stir for 2 hours. Add fresh ether and filter the white solid obtained. Vaccum dry to give the title compound 4-chloro-5-methyl-3-trifluoromethylpyrazole-1-carboxylic acid in 96% yield. LC-MS m/z=242 (M+).
후처리
- filtrationfilter the white solid
- customobtained
- customVaccum dry
출처 및 근거
- ORD 기록
- ord-d2e446811f3a4cb78802b0057c78c1ac
- 출처 데이터셋
- uspto-grants-2009_12
- 특허 번호
- US07635698B2
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