Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → (2-Methyl-imidazol-1-yl)-acetic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Methylimidazole | HCID 12749 | — |
| 반응물 | Methyl bromoacetate | HCID 60984 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (2-Methyl-imidazol-1-yl)-acetic acid methyl ester | HCID 28940036 | 47% |
반응 단계
4 ml of bromo acetic acid methyl ester is dissolved in 30 ml DMF and 5.2 g of 2-methylimidazole and 11.2 g potassium carbonate are added. The reaction mixture is stirred at room temperature for several hours and then subjected to aqueous work up. After removal of the solvent the pure product is obtained by flash chromatography in 47 to 78% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07741488B2 |
| 출처 데이터셋 | uspto-grants-2010_06 |
| ORD ID | ord-0bedc00b6d0b4bcbacdd64180013cb6f |
| 출처 메모 | uspto-grants-2010_06 |