Benzenamine, 3-ethynyl- → HCID 18925061, 화합물
반응식
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][C:8]3[O:14][CH2:13][O:12][C:9]=3[CH:10]=2)[N:5]=[CH:4][N:3]=1.[C:15]([C:17]1[CH:18]=[C:19]([CH:21]=[CH:22][CH:23]=1)[NH2:20])#[CH:16]>C(O)(C)C>[ClH:1].[C:15]([C:17]1[CH:18]=[C:19]([NH:20][C:2]2[C:11]3[C:6](=[CH:7][C:8]4[O:14][CH2:13][O:12][C:9]=4[CH:10]=3)[N:5]=[CH:4][N:3]=2)[CH:21]=[CH:22][CH:23]=1)#[CH:16]참가 물질
4
실험 절차
4-Chloro-6,7-methylenedioxyquinazoline (200 mg, 1.04 mmol) and 3-ethynylaniline (127 mg, 1.09 mmol) were refluxed in 5 mL of isopropyl alcohol for 16 hour, cooled and filtered to afford solid title product which was washed with 10 mL of isopropyl alcohol and dried in vacuo at 70° C., 266 mg (79%); mp >350° C.
후처리
- temperaturecooled
- filtrationfiltered
출처 및 근거
- ORD 기록
- ord-5298b4a80d764f668c6122f520e72669
- 출처 데이터셋
- uspto-grants-2009_12
- 특허 번호
- USRE041065E1
반응 노트
불러오는 중…