HCID 57985899, 화합물 → HCID 57985933, 화합물

반응식

[CH3:1][NH:2][C:3](=[O:21])[CH2:4][CH:5]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:6]1[C:14]2[C:9](=[N:10][CH:11]=[CH:12][CH:13]=2)[NH:8][CH:7]=1.[Cl:22]C1C=CN=C2NC=C(C(C3C=CC=CC=3)C3C(=O)OC(C)(C)OC3=O)C=12>>[Cl:22][C:13]1[CH:12]=[CH:11][N:10]=[C:9]2[NH:8][CH:7]=[C:6]([CH:5]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[CH2:4][C:3]([NH:2][CH3:1])=[O:21])[C:14]=12

참가 물질

반응물 2

HCID 57985899HCID 57985899, 화합물

HCID 68552631HCID 68552631, 화합물

생성물 1

HCID 57985933HCID 57985933, 화합물수율 73%

실험 절차

3-(4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-N-methyl-3-phenyl-propionamide was prepared (73% yield) following the procedure described for preparation of N-methyl-3-phenyl-3-(1H-pyrrolo[2,3-b]pyridin-3-yl)-propionamide in Example 1, using 5-[(4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)-phenyl-methyl]-2,2-dimethyl-[1,3]dioxane-4,6-dione.

출처 및 근거

ORD 기록: ord-c85b69d0b7804d1796766220ae4f2d91
출처 데이터셋: uspto-grants-2009_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07638517B2

반응 노트

불러오는 중…