2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine → N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-benzoyl-2-methoxybenzamide

반응식

[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH2:4][CH2:5][N:6]([CH3:12])[CH2:7]2.[C:13]([C:21]1[CH:22]=[CH:23][C:24]([O:30][CH3:31])=[C:25]([CH:29]=1)[C:26](O)=[O:27])(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH3:12][N:6]1[CH2:5][CH2:4][C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:26](=[O:27])[C:25]2[CH:29]=[C:21]([C:13](=[O:20])[C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[CH:22]=[CH:23][C:24]=2[O:30][CH3:31])[CH2:7]1

참가 물질

반응물 2

HCID 141712692-Methyl-1,2,3,4-tetrahydroisoquinolin-5-amine

HCID 186874585-Benzoyl-2-methoxy-benzoic acid

생성물 1

HCID 18687400N-(2-Methyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-5-benzoyl-2-methoxybenzamide

실험 절차

The title compound was prepared in an analogous manner to Example 1 from 5-amino-2-methyl-1,2,3,4-tetrahydroisoquinoline and 5-benzoyl-2-methoxy-benzoic acid.

출처 및 근거

ORD 기록: ord-126f05e0f3284ab9b358a39ad0cb5cbc
출처 데이터셋: uspto-grants-2000_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06110934

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