Acetonitrile → (2,3-Dichlorophenyl)oxoacetonitrile

HRID 1873058노트

반응식

HRID 1873058 반응식
[Cu]([C:4]#[N:5])C#N.C(#N)C.[Cl:9][C:10]1[C:18]([Cl:19])=[CH:17][CH:16]=[CH:15][C:11]=1[C:12](Cl)=[O:13]>C1(C)C=CC=CC=1>[Cl:19][C:18]1[C:10]([Cl:9])=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12]([C:4]#[N:5])=[O:13]

참가 물질

5

반응물 3

HCID 6342AcetonitrileHCID 179442,3-Dichlorobenzoyl chlorideHCID 178418260HCID 178418260, 화합물

생성물 1

HCID 2735968(2,3-Dichlorophenyl)oxoacetonitrile

시약·촉매·용매 1

HCID 1140Toluene용매2회

실험 절차

In a mixture of 128 gm. of copper cyanide, 120 ml. of acetonitrile and 200 ml. of toluene, the solution of 200 gm. of 2,3-dichlorobenzoylchloride (II) in 250 ml of toluene was added. The reaction mixture was refluxed for 16 hour. After filtration, the solvent was removed under reduced pressure to give 200 ml of oily 2,3-dichlorobenzoyl cyanide (III).

후처리

  1. additionIn a mixture of 128 gm
  2. temperatureThe reaction mixture was refluxed for 16 hour
  3. filtrationAfter filtration
  4. customthe solvent was removed under reduced pressure

출처 및 근거

ORD 기록
ord-eb095ba3eead4a9f8d3860a8dd5e9174
출처 데이터셋
uspto-grants-2000_08
특허 번호
US06111101

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