Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-dimethyl-N-{3-methyl-5-[(6-nitropyridin-3-yl)oxy]phenyl}-1H-pyrazole-5-carboxamide → N-{3-[(6-aminopyridin-3-yl)oxy]-5-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-dimethyl-N-{3-methyl-5-[(6-nitropyridin-3-yl)oxy]phenyl}-1H-pyrazole-5-carboxamide | HCID 57749175 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-{3-[(6-aminopyridin-3-yl)oxy]-5-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide | HCID 57749350 | 107.1% |
반응 단계
In the same manner as in Reference Example 13 and using 1,3-dimethyl-N-{3-methyl-5-[(6-nitropyridin-3-yl)oxy]phenyl}-1H-pyrazole-5-carboxamide (7.63 g, 17.3 mmol), palladium carbon (50% water-containing product, 1.88 g) and methanol (50 mL) as starting materials, the title compound (6.25 g, 88%) was obtained as a pale-yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08304557B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-6e07c7d512194af3a7374910ab217d12 |
| 출처 메모 | uspto-grants-2012_11 |