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HRID 1874362생성일: 2026년 10월 26일

Cesium carbonate → Tert-butyl 3-(6-nitropyridin-3-yloxy)phenylcarbamate

https://huagongshe.com/reaction/1874362

반응식

참여 물질

역할이름HCID투입량
반응물Cesium carbonateHCID 10796—
반응물tert-butyl N-(3-hydroxyphenyl)carbamateHCID 312485—
반응물5-Bromo-2-nitropyridineHCID 817620—
용매DimethylformamideHCID 6228—
생성물Tert-butyl 3-(6-nitropyridin-3-yloxy)phenylcarbamateHCID 5774920966.1%

반응 단계

In the same manner as in Reference Example 33 and using tert-butyl (3-hydroxyphenyl)carbamate (18.9 g, 90.3 mmol), 5-bromo-2-nitropyridine (15.3 g, 75.3 mmol), cesium carbonate (36.9 g, 113 mmol) and N,N-dimethylformamide (150 mL) as starting materials, the title compound (16.5 g, 66%) was obtained as a yellow oil.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08304557B2
출처 데이터셋uspto-grants-2012_11
ORD IDord-9076c05ac0334cb590fecdb3047852eb
출처 메모uspto-grants-2012_11