HCID 18149883, 화합물 → HCID 57749155, 화합물

HRID 1874382노트

반응식

HRID 1874382 반응식
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([O:10][C:11]2[CH:12]=[C:13]([CH:18]=[CH:19][CH:20]=2)[C:14]([O:16][CH3:17])=[O:15])=[N:8][CH:9]=1)([O-])=O>CO.[C].[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([O:10][C:11]2[CH:12]=[C:13]([CH:18]=[CH:19][CH:20]=2)[C:14]([O:16][CH3:17])=[O:15])=[N:8][CH:9]=1

참가 물질

4

반응물 1

HCID 18149883HCID 18149883, 화합물

생성물 1

HCID 57749155HCID 57749155, 화합물수율 100.6%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 887Methanol용매

실험 절차

To a solution of methyl 3-[(5-nitropyridin-2-yl)oxy]benzoate (14.4 g, 52.5 mmol) in methanol (100 mL) was added palladium carbon (50% water-containing product, 1.40 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for 6 hr. The reaction mixture was filtered through celite, and the filtrate was concentrated under reduced pressure, and the residue was dried to give the title compound (12.9 g, quant.) as a yellow oil.

후처리

  1. filtrationThe reaction mixture was filtered through celite
  2. concentrationthe filtrate was concentrated under reduced pressure
  3. customthe residue was dried

출처 및 근거

ORD 기록
ord-06dd6b79f5674dd98d5a162575311ab5
출처 데이터셋
uspto-grants-2012_11
특허 번호
US08304557B2

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