Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chlorobenzyl alcohol → 2-[2-(2-Chloro-benzyloxy)-pyridin-3-yl]-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chlorobenzyl alcohol | HCID 28810 | — |
| 반응물 | 2-(2-chloro-pyridin-3-yl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole | HCID 86652286 | — |
| 생성물 | 2-[2-(2-Chloro-benzyloxy)-pyridin-3-yl]-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole | HCID 58209249 | — |
반응 단계
The title compound was prepared in analogy to Example 1, from 2-(2-chloro-pyridin-3-yl)-1-cyclohexylmethyl-5,6-difluoro-1H-benzoimidazole (Ex. 1, intermediate a) and (2-chloro-phenyl)-methanol (CAS Reg. No. 17849-38-6). Light yellow solid (48%). MS (Turbo Spray): m/z=468.2 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08309581B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-b8bedae4352a41788fc20455d3f13815 |
| 출처 메모 | uspto-grants-2012_11 |