2-(Bromomethyl)tetrahydro-2H-pyran → 2-(4-Chloro-2-methoxy-phenyl)-5,6-difluoro-1-(tetrahydro-pyran-2-ylmethyl)-1H-benzoimidazole
반응식
C1(COC2C(C3N(CC4C=C[C:21]([CH2:24][CH2:25][C:26]([OH:28])=O)=[CH:20][CH:19]=4)C4C=C(F)C(F)=CC=4N=3)=CC=CN=2)CC1.[Cl:35][C:36]1[CH:41]=[CH:40][C:39]([C:42]2[N:46](CC3CCCCC3)[C:45]3[CH:54]=[C:55]([F:59])[C:56]([F:58])=[CH:57][C:44]=3[N:43]=2)=[C:38]([O:60][CH2:61]C2C=CC=CC=2Cl)[CH:37]=1.BrCC1CCCCO1>>[Cl:35][C:36]1[CH:41]=[CH:40][C:39]([C:42]2[N:46]([CH2:19][CH:20]3[CH2:21][CH2:24][CH2:25][CH2:26][O:28]3)[C:45]3[CH:54]=[C:55]([F:59])[C:56]([F:58])=[CH:57][C:44]=3[N:43]=2)=[C:38]([O:60][CH3:61])[CH:37]=1참가 물질
4
