Methyl 3-(bromomethyl)benzoate → 3-[2-(4-Chloro-2-methoxy-phenyl)-5,6-difluoro-benzoimidazol-1-ylmethyl]-benzoic acid methyl ester

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12](CC3C=CC(CCC(O)=O)=CC=3)[C:11]3[CH:25]=[C:26]([F:30])[C:27]([F:29])=[CH:28][C:10]=3[N:9]=2)=[C:4]([O:31][CH2:32]C2CCCC2)[CH:3]=1.ClC1C=CC(C2N(CC3CCCCC3)C3C=C(F)C(F)=CC=3N=2)=C(OCC2C=CC=CC=2Cl)C=1.[CH3:72][O:73][C:74](=[O:83])[C:75]1[CH:80]=[CH:79][CH:78]=[C:77]([CH2:81]Br)[CH:76]=1>>[CH3:72][O:73][C:74](=[O:83])[C:75]1[CH:80]=[CH:79][CH:78]=[C:77]([CH2:81][N:12]2[C:11]3[CH:25]=[C:26]([F:30])[C:27]([F:29])=[CH:28][C:10]=3[N:9]=[C:8]2[C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][C:4]=2[O:31][CH3:32])[CH:76]=1