5-(4-Chlorophenyl)-2-methyl-3-furaldehyde → 1-[5-(4-Chlorophenyl)-2-methyl-3-furyl]-3-methylbutan-1-ol

HRID 1876957

반응식

HRID 1876957 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][C:11]([CH3:13])=[C:10]([CH:14]=[O:15])[CH:9]=2)=[CH:4][CH:3]=1>C([Mg]Br)C(C)C.O1CCCC1>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][C:11]([CH3:13])=[C:10]([CH:14]([OH:15])[CH2:4][CH:5]([CH3:8])[CH3:6])[CH:9]=2)=[CH:4][CH:3]=1

참가 물질

3

반응물 1

HCID 219864715-(4-Chlorophenyl)-2-methyl-3-furaldehyde

생성물 1

HCID 685126271-[5-(4-Chlorophenyl)-2-methyl-3-furyl]-3-methylbutan-1-ol수율 170.5%

시약·촉매·용매 1

HCID 178420648HCID 178420648, 화합물용매

실험 절차

An operation similar to that in Example 3 (2) was performed using 5-(4-chlorophenyl)-2-methyl-3-furaldehyde (1.3 g) and 1N isobutylmagnesium bromide-tetrahydrofuran solution (10 mL) to give the title compound (1.4 g, 85%) as an oil.

출처 및 근거

ORD 기록
ord-a8557d7ed0d441caaabc4bed5d807053
출처 데이터셋
uspto-grants-2012_11
특허 번호
US08309580B2

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