Thionyl Chloride → 3-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuran

HRID 1877066노트

반응식

HRID 1877066 반응식
[CH:1]1([CH:6]([C:8]2[CH:12]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[O:10][C:9]=2[CH3:19])O)[CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:22])=O>C1(C)C=CC=CC=1>[Cl:22][CH:6]([CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[C:8]1[CH:12]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:10][C:9]=1[CH3:19]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 68509772Cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol

생성물 1

HCID 685140893-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuran수율 100%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

To a solution of cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol (0.9 g) in toluene (20 mL) was added thionyl chloride (0.5 mL), and the mixture was stirred at room temperature overnight. The solvent was evaporated under reduced pressure to give the title compound (1.0 g, 100%) as an oil.

후처리

  1. customThe solvent was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-33ed6ed5150244c3820f26b7b43f1c9b
출처 데이터셋
uspto-grants-2012_11
특허 번호
US08309580B2

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