Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 3'-(3-Hydroxypropoxy)biphenyl-3-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 3-Bromo-1-propanol | HCID 12308 | — |
| 반응물 | 3,3'-Biphenyldiol | HCID 69165 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 3'-(3-Hydroxypropoxy)biphenyl-3-ol | HCID 58239599 | — |
반응 단계
26.0 g (0.140 mol) of biphenyl-3,3′-diol and 10.0 g of 3-bromo-1-propanol are dissolved in 300 ml of acetone, and, after addition of 19.3 g (0.140 mol) of potassium carbonate, the mixture is heated under reflux overnight. The batch is subsequently filtered and evaporated, and the residue is chromatographed on silica gel with toluene/ethyl acetate (1:1), giving 3′-(3-hydroxypropoxy)biphenyl-3-ol as colourless crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08313669B2 |
| 출처 데이터셋 | uspto-grants-2012_11 |
| ORD ID | ord-03f122dcbd154e85b85f04a9e58d140a |
| 출처 메모 | uspto-grants-2012_11 |