Potassium Hydroxide → HCID 58345423, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])=[CH:11][C:10]([C:21]([O:23]CC)=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[OH-].[K+]>>[Cl:1][C:2]1[CH:3]=[C:4]([N:8]2[C:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])=[CH:11][C:10]([C:21]([OH:23])=[O:22])=[N:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 14797Potassium Hydroxide

HCID 58345427HCID 58345427, 화합물

생성물 1

HCID 58345423HCID 58345423, 화합물수율 92%

실험 절차

Starting from 240 mg (0.61 mmol) of ethyl 1-(3-chlorophenyl)-5-(2,4-dichloro-phenyl)-1H-pyrazole-3-carboxylate from example 18A and 340.3 mg (6.1 mmol) of potassium hydroxide, 204 mg (0.55 mmol, 92% yield of theory) are obtained as crystals according to the method described in example 7A.

후처리

customare obtained as crystals

출처 및 근거

ORD 기록: ord-e87a488f635648f3bfb28c3f20cad999
출처 데이터셋: uspto-grants-2012_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08314089B2

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